selected publications
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academic article
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article
- A General Small-Angle X-ray Scattering-Based Screening Protocol Validated for Protein-RNA Interactions.
- Ab Initio Prediction of NMR Spin Relaxation Parameters from Molecular Dynamics Simulations.
- Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface.
- Author Correction: Molecular dissection of amyloid disaggregation by human HSP70
- Bioaccumulation of therapeutic drugs by human gut bacteria
- Breaking the protein-RNA recognition code.
- Combining NMR and small angle X-ray and neutron scattering in the structural analysis of a ternary protein-RNA complex.
- Deciphering the protein-RNA recognition code: combining large-scale quantitative methods with structural biology.
- Efficient segmental isotope labeling of multi-domain proteins using Sortase A.
- Emerging RNA-binding roles in the TRIM family of ubiquitin ligases
- Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics.
- Highlight: Young research groups in Germany – continued
- Highlight: young research groups in Germany
- Improved Accuracy from Joint X-ray and NMR Refinement of a Protein-RNA Complex Structure.
- Integrative Structural Biology of Protein-RNA Complexes.
- Local destabilization of the metal-binding region in human copper-zinc superoxide dismutase by remote mutations is a possible determinant for progression of ALS.
- MTMDAT-HADDOCK: high-throughput, protein complex structure modeling based on limited proteolysis and mass spectrometry.
- MTMDAT: Automated analysis and visualization of mass spectrometry data for tertiary and quaternary structure probing of proteins.
- Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1
- Mechanism of riboregulation of p62 protein oligomerisation by vault RNA1-1 in selective autophagy
- Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions
- Molecular dissection of amyloid disaggregation by human HSP70
- Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
- Protein conformational exchange measured by 1H R1ρ relaxation dispersion of methyl groups.
- Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras.
- RNA binding regulates TRIM25-mediated RIG-I ubiquitylation
- RNA regulates Glycolysis and Embryonic Stem Cell Differentiation via Enolase 1
- Resolving the α-glycosidic linkage of arginine-rhamnosylated translation elongation factor P triggers generation of the first ArgRha specific antibody.
- Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins
- Structural Analysis of Protein-RNA Complexes in Solution Using NMR Paramagnetic Relaxation Enhancements.
- Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P.
- Structural Basis of an Asymmetric Condensin ATPase Cycle
- Structural basis for EarP-mediated arginine glycosylation of translation elongation factor EF-P
- Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
- Structural basis for the assembly of the Sxl-Unr translation regulatory complex.
- Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
- Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
- Structural characteristics determine the cause of the low enzyme activity of two thiopurine S-methyltransferase allelic variants: a biophysical characterization of TPMT*2 and TPMT*5.
- Structural features of Argonaute-GW182 protein interactions.
- Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52.
- Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome.
- Structurally derived mutations define congenital heart block-related epitopes within the 200-239 amino acid stretch of the Ro52 protein.
- Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
- Structure and dynamics of the quaternary hunchback mRNA translation repression complex
- Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
- Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless
- Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless
- Structure-based screening of binding affinities via small-angle X-ray scattering
- Structure-based screening of binding affinities via small-angle X-ray scattering.
- Switching the Post-translational Modification of Translation Elongation Factor EF-P
- The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation.
- The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.
- The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.
- The dynamic duo: combining NMR and small angle scattering in structural biology.
- The fellowship of the RING: the RING-B-box linker region interacts with the RING in TRIM21/Ro52, contains a native autoantigenic epitope in Sjögren syndrome, and is an integral and conserved region in TRIM proteins.
- The role of small-angle scattering in structure-based screening applications.
- The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
- Transcriptional regulation of the N ε -fructoselysine metabolism in Escherichia coli by global and substrate-specific cues.
- Transcriptional regulation of the Nε-fructoselysine metabolism in Escherichia coli by global and substrate-specific cues
- Validation and classification of RNA binding proteins identified by mRNA interactome capture
- Validation and classification of RNA binding proteins identified by mRNA interactome capture
- Vault RNA1–1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization