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• A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology.
• Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway.
• Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner.
• Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS.
• BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr³⁴⁸ phosphorylation.
• Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment
• DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
• Decreased plasma C-reactive protein levels in APOE ε4 allele carriers
• Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
• Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease
• Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples
• Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.
• MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation.
• Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease.
• Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ.
• Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models
• S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5
• SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1
• Supervised pathway analysis of blood gene expression profiles in Alzheimer's disease.
• Synaptic dysfunction and septin protein family members in neurodegenerative diseases
• The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.