article

• A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity.
• ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
• CG dinucleotides enhance promoter activity independent of DNA methylation.
• Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.
• Cis-regulatory landscapes of four cell types of the retina.
• GPAT: retrieval of genomic annotation from large genomic position datasets.
• Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters
• Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.
• H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells.
• High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions.
• Interpreting and visualizing ChIP-seq data with the seqMINER software.
• Keys to open chromatin for transcription activation: FACT and Asf1.
• Lessons from genome-wide studies: an integrated definition of the coactivator function of histone acetyl transferases.
• McQ – An open-source multiplexed SARS-CoV-2 quantification platform
• Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo.
• SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers.
• Studying transcription factor function in the genome at molecular resolution.
• Systems biology approaches bring new insights in the understanding of global gene regulatory mechanisms and their deregulation in cancer
• Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans.
• The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.
• The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes.
• Tracking the evolution of cancer methylomes.
• seqMINER: an integrated ChIP-seq data interpretation platform.