article

• A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development.
• Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum.
• Beyond DNA: programming and inheritance of parental methylomes.
• Cell Surface Mechanics Gate Embryonic Stem Cell Differentiation.
• Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development.
• DNA methylation dynamics during the mammalian life cycle.
• Dppa2 and Dppa4 counteract de novo methylation to establish a permissive epigenome for development.
• Dynamic heterogeneity and DNA methylation in embryonic stem cells.
• Epigenetic Inheritance is Gated by Naïve Pluripotency and Dppa2
• Epigenetic editing: Dissecting chromatin function in context
• Epigenetic inheritance is gated by naïve pluripotency and Dppa2
• Genome-Scale CRISPR Screening for Regulators of Cell Fate Transitions.
• Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.
• Identification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF.
• Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.
• Parallel mechanisms of epigenetic reprogramming in the germline.
• Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation.
• Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline.
• Regulatory principles of pluripotency: from the ground state up.
• Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition.
• Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency.
• The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways.
• The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development.
• Tracing the transitions from pluripotency to germ cell fate with CRISPR screening.
• xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function.