selected publications
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article
- A compact Cascade–Cas3 system for targeted genome engineering
- A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species.
- Adaptive evolution of complex innovations through stepwise metabolic niche expansion.
- Anti-CRISPR protein applications: natural brakes for CRISPR-Cas technologies.
- Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides.
- Bacterial evolution of antibiotic hypersensitivity.
- Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action.
- Competition between transposable elements and mutator genes in bacteria.
- Conditional DNA repair mutants enable highly precise genome engineering.
- Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.
- Directed homologous recombination for genome engineering in Escherichia coli.
- Evolthon: A community endeavor to evolve lab evolution
- Genetic Manipulation of a CAST of Characters in a Microbial Community.
- Genome-Wide Abolishment of Mobile Genetic Elements Using Genome Shuffling and CRISPR/Cas-Assisted MAGE Allows the Efficient Stabilization of a Bacterial Chassis.
- Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network.
- Genomewide screen for modulators of evolvability under toxic antibiotic exposure.
- Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance.
- Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations.
- Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs.
- Network-level architecture and the evolutionary potential of underground metabolism.
- Perturbation of iron homeostasis promotes the evolution of antibiotic resistance.
- Phenotypic heterogeneity promotes adaptive evolution.
- Scarless engineering of the Escherichia coli genome.
- System-level genome editing in microbes
- Targeted mutagenesis of multiple chromosomal regions in microbes
- The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse.