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• A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins.
• A careful disorderliness in the proteome: sites for interaction and targets for future therapies.
• A community standard format for the representation of protein affinity reagents.
• A comparative analysis to study editing of small noncoding BC200- and Alu transcripts in brain of prion-inoculated rhesus monkeys (M. Mulatta).
• A million peptide motifs for the molecular biologist.
• A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate.
• A new protein linear motif benchmark for multiple sequence alignment software.
• A regular pattern of two types of 100-residue motif in the sequence of titin.
• A structure filter for the Eukaryotic Linear Motif Resource.
• A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences.
• An estimate of large-scale sequencing accuracy.
• An intrinsically disordered proteins community for ELIXIR.
• An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
• An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.
• Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction.
• Anopheles gambiae SRPN2 facilitates midgut invasion by the malaria parasite Plasmodium berghei.
• Applying motif and profile searches.
• Assignment of the 1H, 15N, and 13C resonances of the C-terminal domain of frataxin, the protein responsible for Friedreich ataxia.
• Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems.
• Attributes of short linear motifs.
• BLAST2SRS, a web server for flexible retrieval of related protein sequences in the SWISS-PROT and SPTrEMBL databases.
• Bacterial alpha2-macroglobulins: colonization factors acquired by horizontal gene transfer from the metazoan genome?
• Base sequence discrimination by zinc-finger DNA-binding domains.
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
• CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals.
• Capturing cooperative interactions with the PSI-MI format.
• Catalytic RNA and the origin of genetic systems.
• Cell regulation: determined to signal discrete cooperation.
• CiliaCarta: An integrated and validated compendium of ciliary genes.
• Clustal W and Clustal X version 2.0.
• Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1
• Degrons in cancer
• Detection of dsRNA-binding domains in RNA helicase A and Drosophila maleless: implications for monomeric RNA helicases.
• Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.
• Discovery of candidate KEN-box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation.
• Divergent evolution of a protein-protein interaction revealed through ancestral sequence reconstruction and resurrection
• Drift and conservation of differential exon usage across tissues in primate species.
• Dystrophin and utrophin: the missing links!
• ELM 2016--data update and new functionality of the eukaryotic linear motif resource.
• ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.
• ELM--the database of eukaryotic linear motifs.
• ELM-the eukaryotic linear motif resource in 2020.
• ELM: the status of the 2010 eukaryotic linear motif resource.
• Elution profile analysis of SDS-induced subcomplexes by quantitative mass spectrometry.
• EpiC: an open resource for exploring epitopes to aid antibody-based experiments.
• Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.
• Evidence for the concerted evolution between short linear protein motifs and their flanking regions.
• Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad.
• Exploring Short Linear Motifs Using the ELM Database and Tools.
• Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega.
• Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region.
• From sequence to structural analysis in protein phosphorylation motifs.
• Gene2EST: a BLAST2 server for searching expressed sequence tag (EST) databases with eukaryotic gene-sized queries.
• Genetic redundancy in vertebrates: polyploidy and persistence of genes encoding multidomain proteins.
• GlobPlot: Exploring protein sequences for globularity and disorder.
• Homology-based method for identification of protein repeats using statistical significance estimates
• How to Annotate and Submit a Short Linear Motif to the Eukaryotic Linear Motif Resource.
• How viruses hijack cell regulation.
• Hunting for Cis-Regulatory Elements in Proteins.
• Improved sensitivity of profile searches through the use of sequence weights and gap excision.
• Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.
• KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors.
• KH domains within the FMR1 sequence suggest that fragile X syndrome stems from a defect in RNA metabolism.
• Linear motifs confer functional diversity onto splice variants.
• Linear motifs: lost in (pre)translation.
• Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation.
• Metabolic complexity in the RNA world and implications for the origin of protein synthesis.
• Metabolic shifts in residual breast cancer drive tumor recurrence.
• Mimicry of Short Linear Motifs by Bacterial Pathogens: A Drugging Opportunity.
• Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
• Motif switches: decision-making in cell regulation.
• Multiple sequence alignment using ClustalW and ClustalX.
• Multiple sequence alignment with Clustal X.
• Multiple sequence alignment with the Clustal series of programs.
• NINL and DZANK1 Co-function in Vesicle Transport and Are Essential for Photoreceptor Development in Zebrafish.
• Non-muscle and smooth muscle myosin light chain kinases: no end in sight.
• Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300.
• Object-oriented parsing of biological databases with Python.
• PDBe-KB: a community-driven resource for structural and functional annotations.
• PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins.
• PH domain: the first anniversary.
• PairWise and SearchWise: finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames.
• Patterns and clusters within the PSM column in TiBS, 1992-2004.
• Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins.
• Phospho.ELM: a database of phosphorylation sites--update 2008.
• Phospho.ELM: a database of phosphorylation sites--update 2011.
• Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors.
• Possible editing of Alu transcripts in blood cells of sporadic Creutzfeldt-Jakob disease (sCJD).
• Prion infected rhesus monkeys to study differential transcription of Alu DNA elements and editing of Alu transcripts in neuronal cells and blood cells.
• Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis.
• Proposed structure for the DNA-binding domain of the helix-loop-helix family of eukaryotic gene regulatory proteins.
• Protein disorder prediction: Implications for structural proteomics
• Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer?
• ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome.
• Protruding domain of tomato bushy stunt virus coat protein is a hitherto unrecognized class of jellyroll conformation.
• RACK1 research - ships passing in the night?
• Rop/helix-loop-helix similarity.
• RuNAway Disease: A two cycle model for transmissible spongiform encephalopathies (TSEs) wherein SINE proliferation drives PrP overproduction.
• SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions.
• Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications.
• Short linear motif core and flanking regions modulate retinoblastoma protein binding affinity and specificity.
• Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation.
• Solution structure of the DNA-binding domain of the yeast transcriptional activator protein GCN4.
• Solution structure of the basic region from the transcriptional activator GCN4.
• Structure of the dsRNA binding domain of E. coli RNase III.
• Systematic discovery of new recognition peptides mediating protein interaction networks.
• The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators.
• The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor.
• The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre.
• The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.
• The Eukaryotic Linear Motif resource: 2022 release.
• The Gene Ontology of eukaryotic cilia and flagella.
• The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid.
• The PHD finger: implications for chromatin-mediated transcriptional regulation.
• The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.
• The eukaryotic linear motif resource - 2018 update.
• The eukaryotic linear motif resource ELM: 10 years and counting.
• The evolution of titin and related giant muscle proteins.
• The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin.
• The identification of short linear motif-mediated interfaces within the human interactome.
• The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly
• The solution structure of a leucine-zipper motif peptide.
• The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome.
• The switches.ELM resource: a compendium of conditional regulatory interaction interfaces.
• The transience of transient overexpression.
• Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
• Transcription of Alu DNA elements in blood cells of sporadic Creutzfeldt-Jakob disease (sCJD).
• Understanding eukaryotic linear motifs and their role in cell signaling and regulation.
• Using CLUSTAL for multiple sequence alignments.
• Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis.
• iELM--a web server to explore short linear motif-mediated interactions.