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• A GyrB-GyrA fusion protein expressed in yeast cells is able to remove DNA supercoils but cannot substitute eukaryotic topoisomerase II
• A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding
• Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology
• Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils
• Cloning, functional analysis and post-transcriptional regulation of a type II DNA topoisomerase from Leishmania infantum. A new potential target for anti-parasite drugs
• Condensin minimizes topoisomerase II‐mediated entanglements of DNA in vivo
• Condensin pinches a short negatively supercoiled DNA loop during each round of ATP usage
• DNA Topology and Global Architecture of Point Centromeres
• DNA knots occur in intracellular chromatin.
• DNA knots reveal a chiral organization of DNA in phage capsids
• DNA transport by a type II DNA topoisomerase: Evidence in favor of a two-gate mechanism
• DNA transport by a type II topoisomerase: Direct evidence for a two-gate mechanism
• Dysbiosis and relapse-related microbiome in inflammatory bowel disease: A shotgun metagenomic approach
• Electrophoretic analysis of the DNA supercoiling activity of DNA gyrase
• Expression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility
• Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells
• Fractal dimension and localization of DNA knots
• Genome urbanization: clusters of topologically co-regulated genes delineate functional compartments in the genome of Saccharomyces cerevisiae.
• Human gut metatranscriptome changes induced by a fermented milk product are associated with improved tolerance to a flatulogenic diet
• In silico, in vitro and in vivo imageries of type II topoisomerases: Comment on “Disentangling DNA molecules” by Alexander Vologodskii
• Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
• Keeping intracellular DNA untangled: A new role for condensin?
• Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids
• Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes
• Production of highly knotted DNA by means of cosmid circularization inside phage capsids
• Quantitative disclosure of DNA knot chirality by high-resolution 2D-gel electrophoresis.
• Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
• Structure and Chromosomal Organization of Yeast Genes Regulated by Topoisomerase II
• The capture of a DNA double helix by an ATP-dependent protein clamp: A key step in DNA transport by type II DNA topoisomerases
• The mechanisms of DNA topoisomerases
• The path of the DNA along the dimer interface of topoisomerase II
• The torsional state of DNA within the chromosome
• Topoisomerase II is required for the production of long Pol II gene transcripts in yeast
• Topoisomerase II minimizes DNA entanglements by proofreading DNA topology after DNA strand passage
• Topoisomerase II regulates yeast genes with singular chromatin architectures
• Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA
• Topoisomerase II: A fitted mechanism for the chromatin landscape
• Topoisomerases
• Topology of viral DNA
• Transcriptional inhibition by DNA torsional stress
• Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA
• Varying levels of positive and negative supercoiling differently affect the efficiency with which topoisomerase II catenates and decatenates DNA