selected publications
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article
- A Family of Pyrazinone Natural Products from a Conserved Nonribosomal Peptide Synthetase in Staphylococcus aureus
- A general strategy to characterize calmodulin–calcium complexes involved in CaM–target recognition: DAPK and EGFR calmodulin binding domains interact with different calmodulin–calcium complexes
- A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria
- Absolute Proteome Composition and Dynamics during Dormancy and Resuscitation of Mycobacterium tuberculosis.
- Adaptive laboratory evolution of microbial co‐cultures for improved metabolite secretion
- Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response
- Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism.
- Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine
- Dynamic exometabolome analysis reveals active metabolic pathways in non-replicating mycobacteria
- Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut
- Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice
- Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis.
- High coverage metabolomics analysis reveals phage-specific alterations to Pseudomonas aeruginosa physiology during infection
- Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter
- Insights from pharmacokinetic models of host-microbiome drug metabolism
- Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of Mycobacterium tuberculosis during Early Macrophage Infection
- Mapping human microbiome drug metabolism by gut bacteria and their genes
- Metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation
- Metabolite profiling and peptidoglycan analysis of transient cell wall-deficient bacteria in a new Escherichia coli model system.
- Model-based integration of genomics and metabolomics reveals SNP functionality in Mycobacterium tuberculosis
- Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation
- Mycobacterium tuberculosis phosphoenolpyruvate carboxykinase is regulated by redox mechanisms and interaction with thioredoxin.
- Next-Generation "-omics" Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa.
- Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations
- Nontargeted profiling of coenzyme A thioesters in biological samples by tandem mass spectrometry.
- PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
- Quantification and mass isotopomer profiling of α-keto acids in central carbon metabolism.
- Separating host and microbiome contributions to drug pharmacokinetics and toxicity
- Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines
- The Stringent Response Determines the Ability of a Commensal Bacterium to Survive Starvation and to Persist in the Gut
- The gut microbiome in solid organ transplantation
- Towards a mechanistic understanding of reciprocal drug–microbiome interactions