selected publications
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academic article
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article
- 1H, 13C, and 15N chemical shift assignments for the Eps15-EH2-stonin 2 complex.
- A TROSY relayed HCCH-COSY experiment for correlating adenine H2/H8 resonances in uniformly 13C-labeled RNA molecules.
- A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT
- A reducing milieu renders cofilin insensitive to phosphatidylinositol 4,5-bisphosphate (PIP2) inhibition.
- A structure refinement protocol combining NMR residual dipolar couplings and small angle scattering restraints.
- A suite of solid-state NMR experiments for RNA intranucleotide resonance assignment in a 21 kDa protein-RNA complex.
- A target function for quaternary structural refinement from small angle scattering and NMR orientational restraints.
- An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution.
- Automated structure modeling of large protein assemblies using crosslinks as distance restraints.
- Backbone 1H, 13C, and 15N resonance assignments of the N-terminal domain of FKBP38 (FKBP38NTD).
- Bioaccumulation of therapeutic drugs by human gut bacteria
- DENR–MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation
- De novo structure determination from residual dipolar couplings by NMR spectroscopy.
- Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences.
- Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling.
- Establishing the yeast Saccharomyces cerevisiae as a system for expression of human proteins on a proteome-scale.
- Extending the size of protein-RNA complexes studied by nuclear magnetic resonance spectroscopy.
- Fast identification of folded human protein domains expressed in E. coli suitable for structural analysis.
- Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction
- Functional role of the flexible N-terminal extension of FKBP38 in catalysis.
- Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromes.
- Heteronuclear relaxation study of the PH domain of beta-spectrin: restriction of loop motions upon binding inositol trisphosphate.
- Improving the sensitivity of FT-NMR spectroscopy by apodization weighted sampling
- Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1
- Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.
- NMR approaches for structural analysis of multidomain proteins and complexes in solution.
- NMR assignment of the Drosophila Argonaute2 PAZ domain.
- NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease.
- New NMR assignment 1H, 13C, and 15N assignment of the second PH domain of human pleckstrin (234-350).
- Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
- Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity.
- Phosphorylation of LRP1 regulates the interaction with Fe65.
- Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras.
- RNA structure determination by solid-state NMR spectroscopy.
- Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein.
- Resolving the α-glycosidic linkage of arginine-rhamnosylated translation elongation factor P triggers generation of the first ArgRha specific antibody.
- Screening of fusion partners for high yield expression and purification of bioactive viscotoxins.
- Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins
- Signal selection in high-resolution NMR by pulsed field gradients.
- Speeding up biomolecular NMR spectroscopy.
- Structural Analysis of Protein-RNA Complexes in Solution Using NMR Paramagnetic Relaxation Enhancements.
- Structural Basis of an Asymmetric Condensin ATPase Cycle
- Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation.
- Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
- Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
- Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
- Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
- Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme.
- Structure and VP16 binding of the Mediator Med25 activator interaction domain.
- Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
- Structure and dynamics of the human pleckstrin DEP domain: distinct molecular features of a novel DEP domain subfamily.
- Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
- Structure and dynamics of the quaternary hunchback mRNA translation repression complex.
- Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain.
- Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
- Structure of the K-turn U4 RNA: a combined NMR and SANS study.
- Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
- Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless
- Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1
- Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1
- The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin.
- The structure of the SOLE element of oskar mRNA.
- The structure of the box C/D enzyme reveals regulation of RNA methylation.
- The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
- The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy.
- Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
- ¹H, ¹³C, and ¹⁵N chemical shift assignments of the phosphotyrosine binding domain 2 (PTB2) of human FE65.