selected publications
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academic article
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article
- A Simple and Direct Assay for Monitoring Fatty Acid Synthase Activity and Product-Specificity by High-Resolution Mass Spectrometry
- A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.
- A novel pathway of ceramide metabolism in Saccharomyces cerevisiae.
- A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking.
- Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling.
- Accurate quantification of lipid species affected by isobaric overlap in Fourier-transform mass spectrometry
- Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases.
- Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumorinitiating cells
- Adipose MDM2 regulates systemic insulin sensitivity
- An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER.
- Analysis of lipid experiments (ALEX): a software framework for analysis of high-resolution shotgun lipidomics data.
- Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning.
- Automated, parallel mass spectrometry imaging and structural identification of lipids
- Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets
- Characterization of yeast mutants lacking alkaline ceramidases YPC1 and YDC1.
- Charting molecular composition of phosphatidylcholines by fatty acid scanning and ion trap MS3 fragmentation.
- Collision-induced dissociation pathways of yeast sphingolipids and their molecular profiling in total lipid extracts: a study by quadrupole TOF and linear ion trap-orbitrap mass spectrometry.
- Composition, structure and properties of POPC-triolein mixtures. Evidence of triglyceride domains in phospholipid bilayers.
- Compositional and structural characterization of monolayers and bilayers composed of native pulmonary surfactant from wild type mice.
- Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MS(ALL).
- Comprehensive lipidome analysis by shotgun lipidomics on a hybrid quadrupole-orbitrap-linear ion trap mass spectrometer.
- Dairy-Derived Emulsifiers in Infant Formula Show Marginal Effects on the Plasma Lipid Profile and Brain Structure in Preterm Piglets Relative to Soy Lecithin
- Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy.
- Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
- Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans.
- Easy, Fast, and Reproducible Quantification of Cholesterol and Other Lipids in Human Plasma by Combined High Resolution MSX and FTMS Analysis
- Exogenous ether lipids predominantly target mitochondria.
- Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans.
- Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae.
- Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance.
- Generic sorting of raft lipids into secretory vesicles in yeast.
- Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry.
- High-content screening of yeast mutant libraries by shotgun lipidomics.
- High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry.
- Homeoviscous Adaptation and the Regulation of Membrane Lipids.
- Identification and Annotation of Lipid Species in Metabolomics Studies Need Improvement.
- Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis
- LAMTOR/Ragulator regulates lipid metabolism in macrophages and foam cell differentiation
- Lipid composition can predict mice native pulmonary surfactant membranes. 2. Fluid phase coexistence in bilayers and monolayers
- Lipid droplet consumption is functionally coupled to vacuole homeostasis independent of lipophagy
- Lipid informatics
- Lipid molecular timeline profiling reveals diurnal crosstalk between the liver and circulation
- Lipid profiling by multiple precursor and neutral loss scanning driven by the data-dependent acquisition.
- LipidCreator workbench to probe the lipidomic landscape
- Lipidomics needs more standardization
- MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes
- Membrane lipidome of an epithelial cell line.
- Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.
- Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism.
- Modulation of the Lactobacillus acidophilus La-5 lipidome by different growth conditions.
- Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids
- Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans
- Orm family proteins mediate sphingolipid homeostasis.
- Osmolality, temperature, and membrane lipid composition modulate the activity of betaine transporter BetP in Corynebacterium glutamicum.
- PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast.
- Pex35 is a regulator of peroxisome abundance.
- Phosphoproteomic Analysis across the Yeast Life Cycle Reveals Control of Fatty Acyl Chain Length by Phosphorylation of the Fatty Acid Synthase Complex
- Polyene-lipids: a new tool to image lipids.
- Profiling of lipid species by normal-phase liquid chromatography, nanoelectrospray ionization, and ion trap-orbitrap mass spectrometry.
- Proposal for a common nomenclature for fragment ions in mass spectra of lipids
- Quality control requirements for the correct annotation of lipidomics data
- Quantification of Cholesterol and Cholesteryl Ester by Direct Flow Injection High-Resolution Fourier Transform Mass Spectrometry Utilizing Species-Specific Response Factors
- Quantitative Profiling of Long-Chain Bases by Mass Tagging and Parallel Reaction Monitoring.
- Quantitative analysis of proteome and lipidome dynamics reveals functional regulation of global lipid metabolism.
- Quantitative lipidomics reveals age-dependent perturbations of whole-body lipid metabolism in ACBP deficient mice.
- Quantitative profiling of PE, MMPE, DMPE, and PC lipid species by multiple precursor ion scanning: a tool for monitoring PE metabolism.
- Regulation of lipid droplets by metabolically controlled Ldo isoforms
- Reporting of lipidomics data should be standardized.
- Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated.
- Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network.
- Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
- Seipin is required for converting nascent to mature lipid droplets.
- Shotgun lipidomic analysis of chemically sulfated sterols compromises analytical sensitivity: Recommendation for large-scale global lipidome analysis.
- Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death
- Simple Targeted Assays for Metabolic Pathways and Signaling
- Specific lipids modulate the transporter associated with antigen processing (TAP).
- Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4.
- Structural characterization of ether lipids from the archaeon Sulfolobus islandicus by high-resolution shotgun lipidomics.
- Structural characterization of suppressor lipids by high-resolution mass spectrometry.
- The Effects of Temperature and Growth Phase on the Lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii.
- The GARP complex is required for cellular sphingolipid homeostasis.
- The lipidomes of vesicular stomatitis virus, semliki forest virus, and the host plasma membrane analyzed by quantitative shotgun mass spectrometry.
- The role of lipids and salts in two-dimensional crystallization of the glycine-betaine transporter BetP from Corynebacterium glutamicum.
- Total Fatty Acid Analysis of Human Blood Samples in One Minute by High-Resolution Mass Spectrometry
- Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
- Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures
- Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
- Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
- Yeast cells lacking all known ceramide synthases continue to make complex sphingolipids and to incorporate ceramides into glycosylphosphatidylinositol (GPI) anchors.
- Yeast lipids can phase-separate into micrometer-scale membrane domains.